Public-Private Partnerships are seen as mechanisms that offer the promise to strengthen government's policy implementation capacity and its ability to deliver services efficiently, effectively, economically and equitably (4Es) to communities. HIV / AIDS-related problems add to the complexities associated with building partnerships and networks as it demands a shift towards horizontal and broader based policy issues that show no respect to boundaries or do not fit neatly into areas of jurisdiction. Traditional models that described public and private relations have become obsolete, forcing governments to revisit their role and the type of outcomes they want to achieve. The symbiotic relationship between the economy, society, political philosophy and public finances increase the difficulty of finding a balance between the relative sizes of public and private health sectors steered by supply and demand functions, against a backgroun